Pharmacogenetic guidance: individualized medicine promotes enhanced pain outcomes

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Pharmacogenetic guidance: individualized medicine promotes enhanced pain outcomes

The use of pharmacogenomics has become more prevalent over the past several years in treating many disease states. Several cytochrome P450 enzymes play a role in the metabolism of many pain medications including opioids and antidepressants. Noncytochrome P450 enzymes such as methylenetetrahydrofolate reductase (MTHFR) and catechol-O-methyl transferase (COMT) also play a role in the explanation ...

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ژورنال

عنوان ژورنال: Journal of Pain Research

سال: 2017

ISSN: 1178-7090

DOI: 10.2147/jpr.s144560